Should we be using 5-HT3 antagonists as first line antiemetic therapy in cisplatin-based chemotherapy?
نویسندگان
چکیده
منابع مشابه
Antiemetic prophylaxis for office-based surgery: are the 5-HT3 receptor antagonists beneficial?
BACKGROUND Office-based surgery has become increasingly popular because of its cost-saving potential. However, the occurrence of postoperative nausea and vomiting (PONV) can delay patient discharge. Prophylaxis using a combination of antiemetic drugs has been suggested as an effective strategy for minimizing PONV. The authors designed this randomized, double-blinded, placebo-controlled study to...
متن کاملManagement of chemotherapy induced emesis
Important progress has been achieved in the last few years in the prevention of chemotherapy-induced nausea and vomiting thanks to the introduction in clinical practice first of the 5-HT3 antagonists and of the NK1 antagonists more recently. To prevent acute emesis induced by cisplatin/moderately emetogenic chemotherapy, a combination of aprepitant plus a 5-HT3 antagonist and dexamethasone/a 5-...
متن کاملShould atenolol still be recommended as first-line therapy for primary hypertension?
antihypertensive treatment should reduce the incidence of cardiovascular morbidity and mortality as well as total mortality. For four decades, beta-blockers have been widely used for the treatment of hypertension and are still proposed as first-line drugs in national and international guidelines. Numerous prospective, randomised studies have established beyond any doubt the efficacy of beta-blo...
متن کاملShould atrial fibrillation ablation be considered first-line therapy for some patients? Why Atrial Fibrillation Ablation Should Be Considered First-Line Therapy for Some Patients
Atrial fibrillation (AF) is an increasingly common disease that affects patient morbidity and mortality. To date, treatments of AF have been frustrating, serving at best to palliate this arrhythmia. AF ablation, on the other hand, has emerged as a promising new treatment strategy. In contrast to rate control or antiarrhythmic drugs, ablation offers the possibility of a lasting cure. When ablati...
متن کاملAntiemetic therapy in patients receiving cancer chemotherapy.
PURPOSE/OBJECTIVES To examine the currently available antiemetic medications and review their uses in the treatment of chemotherapy-induced nausea and vomiting (NV). DATA SOURCES Published articles and book chapters. DATA SYNTHESIS NV is a common yet potentially serious side effect of chemotherapy. Nurses must understand the physiology of NV, its impact on patients, and the proper use of an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1993
ISSN: 0923-7534
DOI: 10.1093/oxfordjournals.annonc.a058531